The recommendations for dietitians and other members of the metabolic team to follow when managing the care of women with MSUD before and during pregnancy and after delivery are:
- Provide individualized pregnancy planning information to all women with MSUD of childbearing age and update when pregnancy is confirmed.
- Adjust dietary intake to allow blood LEU concentrations to be in the 100-300μM range and VAL and ILE in the upper range of normal (200- 400μM) throughout pregnancy
- Provide individualized dietary guidance so that nutrient intake meets the changing needs of each phase of pregnancy and the postpartum period.
- Provide nutrient, clinical and biochemical monitoring during all phases of pregnancy and the postpartum period.
- For the woman with MSUD who wishes to breast feed, closely monitor her diet and laboratory markers in addition to her infant’s growth and development.
The workgroup of dietitians who have been contributing to this effort include the following: Barbara Marriage, Courtney Allgeier, Beth Ogata, Julie McClure, Surekha Pendyal, Nikki Drilias and Dianne Frazier. A notice will be sent when the updates to the guideline and toolkit are finalized and published.